Can fenbendazole cause liver toxicity in humans?

Although fenbendazole is generally well tolerated, there have been reports of elevated liver enzymes from the use of Fenbendazole, as well as the similar human medications mebendazole and albendazole.

Therefore, patients should get a blood panel that includes the liver enzymes of AST, ALT, Alkaline Phosphatase, before taking Fenbendazole.  

Liver enzymes may be elevated from cancer treatments, alcohol use, certain medications, and cancer itself.  

Elevated liver enzymes indicate a liver that is stressed and inflamed, and adding to its burden with Fenbendazole would not be recommended.

If a patient has elevated liver enzymes, liver metastasis, or liver diseases, it is important to work with a health professional who is familiar with the use of Fenbendazole and can advise whether it can be used and/or monitor lab values.

Generally, for those with normal lab values, after one month of Fenbendazole treatment, patients should get a comprehensive metabolic panel (CMP). This standard blood test will check the liver and kidney function to assure that the patient is tolerating Fenbendazole without any concerning impacts on the vital organs.

For patients who wish to receive individualized guidance, education, and lab monitoring, it is best to consult an integrative oncology healthcare professional.