Fenbendazole For Cancer - Step By Step Guide (2025)

Medically Reviewed By Dr. Paul Hetrick, PharmD

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Dr. Paul Hetrick is a licensed pharmacist with extensive professional experience across various fields.
He currently resides and practices in North Carolina. Dr. Hetrick earned his BS in Biology from the University of North Carolina at Chapel Hill and his PharmD from Campbell University College of Pharmacy & Health Sciences. He holds several certifications, including a license as a pharmacist and a Pharmacy-Based Immunization Delivery Certification.
Dr. Hetrick is affiliated with the American Pharmacists Association (APhA) and the North Carolina Association of Pharmacists (NCAP).

Fenbendazole, a common veterinary deworming medication, has recently gained significant attention in the field of cancer treatment in light of fenbendazole cancer success stories.

One of the most recognized success stories is that of Joe Tippens, who was diagnosed with stage 4 small cell lung cancer and given just three months to live. Tippens began taking fenbendazole (Panacur C), a dog dewormer, along with several supplements. Remarkably, his subsequent PET scan showed significant improvement, and within months, he was declared cancer-free.

In this comprehensive guide, we’ll explore the fenbendazole cancer protocol, examining how this drug might fight cancer, its potential benefits, and important considerations for those interested in this alternative treatment approach.

Fenbendazole for Cancer: A Simple Step-by-Step Protocol Guide

The basic fenbendazole protocol people follow is surprisingly simple and includes a few added supplements to the fenbendazole:

1. Fenbendazole: One Packet a Day

Fenbendazole which has 222mg of Fenbendazole per gram: one packet of powder per day for seven days a week. It can be mixed with food such as yogurt or simply taken by itself.

It is advised to only purchase from brands that are regulated and that have been consistent in third-party lab results- Panacur C and Safeguard.

If you’re interested in learning more about sourcing Fenbendazole, you can find a list of products and resources on our Fenbendazole Cancer Protocol Products page.

2. Curcumin: 600 mg a Day

600 mg per day of bioavailable curcumin, which is the active agent in the herb turmeric. Curcumin may help increase healthy p53 levels, and it has been shown to be a potentially effective cancer therapy supplement.

3. CBD Oil: 25mg

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25 mg, taken sublingually (under the tongue). The full spectrum CBD oil should be high-purity level broad-spectrum. CBD has been shown to potentially modulate tumor growth.

A nurse’s tip:

It is important to choose the right CBD for medical use: flower-derived, lab-tested, organic, whole-spectrum.
To enhance CBD healing response for cancer symptoms, slowly increase to .5ml of CBD twice daily for a total of 50 mg. (In a product of 1500mg CBD: 1mL = 50mg CBD)

Some people using this protocol use CBD oil, while others choose to add THC. If you are considering adding THC, it is advised to use a Medical Cannabis Professional. Click here to speak with a nurse.

4. Berberine: 2-3 times a day

Berberine has shown important anti-tumor effects in numerous studies. These studies reported that Berberine could prevent the multiplication of cancer cells and inhibit metastasis and the spread of cancer cells. Berberine can work with Fenbendazole to further limit the cancer cell’s ability to take up glucose. This way, cancer cells are weakened and starved.

1000mg to 1500mg per day in doses of 500mg taken 2-3 times daily taken before meals

5. Quercetin: 1-2 a day

Due to its antioxidant, anti-tumor, and anti-inflammatory activity, quercetin has been studied extensively. Quercetin can inhibit the spread of many cancers, such as prostate, cervical, lung, breast, and colon. Quercetin is not harmful to healthy cells yet powerful against cancer cells, making it a good candidate for a supplementary factor along with other anticancer medications.

The typical dosage of quercetin is 500mg to 1000mg per day, typically divided into two to three doses.

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Scientific Data on Fenbendazole for Cancer Treatment

As surprising as it sounds, there is documented research about deworming medications and their effect on cancer. This dry and tasteless Fenbendazole powder has been shown to exhibit “significant inhibition of tumor growth” when supplemented with vitamins A, D, E, K, and B.

In recent years, scientists have ramped up their efforts to study Fenbendazole, also called FenBen/FBZ, in clinical trials. The most recent studies have also shown Fenbendazole can potentially be used to treat pancreatic, ovarian and colorectal cancer.

Fenbendazole is a triple-threat to cancer: it kills cancer cells in three significant ways:

It destroys microtubules that sustain the structure of the cancer cell and its ability to divide and multiply rapidly.
It interrupts the cancer cells’ ability to process sugar, and cancer cells must metabolize sugar to survive.
It boosts the production of a cancer-killing gene called p53; a gene cancer patients may lack. When p53 becomes mutated or can’t keep cancer cells in check, cancer cells can proliferate.

The dewormer also works against parasites, which might be the origin of some cancers.

Other Research That Supports the Use of De-Wormers for Cancer

There’s another “sister” drug of Fenbendazole, called Mebendazole, a de-wormer medication prescribed to treat parasitic worm infections in humans. Mebendazole has shown promising results in treating cancer (Lung, Melanoma, Glioblastoma, Colon, and others).

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Fenbendazole - frequently asked questions

Can fenbendazole be taken in tablet, liquid or powder?

Fenbendazole is available in liquid (Safeguard) and powder (Panacur). There may be other formulations available, but those are the primary products that patients are using.

Is it safe for humans to take fenbendazole?

Since fenbendazole is a veterinary medicine, and is not licensed for human use and there is no specific human safety data available. The similar human forms of this class of medications, mebendazole and albendazole, have been used for parasitic infections for many years and have a good safety record. Fenbendazole has been reported to have a very low degree of toxicity and a high degree of safety in animal experiments.

Is fenbendazole toxic for the liver?

Although fenbendazole is generally well tolerated, there have been reports of elevated liver enzymes from the use of fenbendazole, as well as the human medications mebendazole and albendazole. For this reason, it is essential to provide your Heal Navigator nurse with laboratory reports, a current medication/trreatment list, and medical history, so the safety risks for each individual can be assessed and discussed.

I’ve found a Fenbendazole brand which is not made by Merck, is it ok?

There are a variety of opinions on which product is best, but no research exists that compares the effectiveness of various formulations in humans. Merck and Safeguard are well established companies whose products have been safety tested in animals and used by veterinarians for many years. The Happy Healing company states that their products are manufactured by a FDA registered facility and are quality tested to be pure and free of contaminants.

Would the fenbendazole protocol work with conventional treatment? - chemotherapy?

Yes, fenbendazole has the potential to synergize with conventional treatments, and possibly enhance treatment response. Some aspects of the protocol, such as vitamin E and curcumin, may interfere with chemotherapy and radiation due to their anti-oxidant properties. This will be discussed during your consultation with a Heal Navigator nurse.

Some people take it 3 day on 4 off, some 1 gram a day, some 2 or even 4 grams a day. What is the correct dosage?

Joe Tippens, who popularized the use of Fenbendazole for cancer, recommends 222 mg for three consecutive days, then four days off. There are many people who take larger doses, more frequently. Since Fenbendazole is not licensed for the treatment of cancer in humans, there is no correct dose that is supported by research, pharmacists or physicians. The dose you choose to take should be assessed based on your other medications and treatments, your type of cancer, prognosis, organ function and lab values.

How long do I need to be on this protocol?

This will be up to you based on your treatment response to the protocol. It is reported that Joe Tippens continues to use the protocol for prevention.

How do I know when it is time to dose up?

This is an individual decision based on treatment response, tolerance, other treatments/medications and lab values. Your Heal Navigator nurse will discuss this with you at the time of your consultation.

How effective is fenbendazole for cancer treatment in humans?

While fenbendazole has shown some promising results in preclinical studies, its effectiveness for cancer treatment in humans was not tested in clinical trials. Patients considering fenbendazole for cancer should consult a healthcare provider.

Will Fenbendazole help my dog?

When diagnosed with cancer, fenbendazole was suggested to Joe Tippens by an animal scientist, who observed its ability to shrink tumors in animals. Fenbendazole is prescribed by veterinarians, and is believed to be safe for short term use for parasitic infections. The nurses with Heal Navigator are not able to consult about the use of fenbendazole for dogs.

Fenbendazole Cancer Protocol Testimonials

Laurie was battling triple-negative breast cancer. She began chemotherapy and was adding high amounts of Fenbendazole daily. “I believe that the combination of Fenbendazole and chemo worked very well.”

Read more Fenbendazole testimonials here.

Fenbendazole Cancer Protocol- Relevant Research and News

Repurposing Drugs in Oncology (ReDO)—mebendazole as an anti-cancer agent

Mebendazole, a well-known anti-helminthic drug in wide clinical use, has anti-cancer properties that have been elucidated in a broad range of pre-clinical studies across a number of different cancer types. Significantly, there are also two case reports of anti-cancer activity in humans. The data are summarised and discussed in relation to suggested mechanisms of action. Based on the evidence presented, it is proposed that mebendazole would synergise with a range of other drugs, including existing chemotherapeutics, and that further exploration of the potential of mebendazole as an anti-cancer therapeutic is warranted.

Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo

We have found that mebendazole (MZ), a derivative of benzimidazole, induces a dose- and time-dependent apoptotic response in human lung cancer cell lines. In this study, MZ arrested cells at the G(2)-M phase before the onset of apoptosis, as detected by using fluorescence-activated cell sorter analysis. MZ treatment also resulted in mitochondrial cytochrome c release, followed by apoptotic cell death. Additionally, MZ appeared to be a potent inhibitor of tumor cell growth with little toxicity to normal WI38 and human umbilical vein endothelial cells. When administered p.o. to nu/nu mice, MZ strongly inhibited the growth of human tumor xenografts and significantly reduced the number and size of tumors in an experimental model of lung metastasis. In assessing angiogenesis, we found significantly reduced vessel densities in MZ-treated mice compared with those in control mice. These results suggest that MZ is effective in the treatment of cancer and other angiogenesis-dependent diseases.

Fenbendazole Enhancing Anti-Tumor Effect: A Case Series

Background: Fenbendazole (FBZ) is a cheap and readily available anti-parasitic commonly used in veterinary medicine. FBZ belongs to the benzimidazole drug class which destabilize microtubules through a mechanism similar to the anti-oncogenic vinca alkaloids. Although there are no reported cases in the literature, there have been several anecdotal stories published on website blogs with individuals praising its ability to treat a wide variety of cancers.

Case Presentations: Herein we describe the cases of three patients with various genitourinary malignancies who demonstrated complete response after receiving FBZ therapy as a single or supplementary chemotherapeutic agent. In two patient scenarios, they had experienced progression of metastatic disease despite multiple lines of therapy prior to initiation of FBZ. No side effects from FBZ were reported.

Conclusion: FBZ appears to be a potentially safe and effective antineoplastic agent that can be repurposed for human use in treating genitourinary malignancies. Further research is necessary to define the role of FBZ as a chemotherapeutic option.

Fenbendazole for Cancer:
Comprehensive Protocol Guide