Can fenbendazole have any effects on the kidney?

Fenbendazole is primarily used as an anthelmintic, meaning it's used to treat infections caused by parasites, such as worms, in animals. 

It is in the drug class of benzimidazoles, which includes the very similar medication mebendazole, increasingly prescribed by integrative doctors for humans.  

There is growing interest in the potential of benzimidazoles as a cancer treatment, particularly in conjunction with other medications.

Regarding its effects on the kidneys specifically, there isn't extensive research on this topic, especially in humans. Most studies focus on its efficacy against parasites and its potential anticancer properties. However, like any medication, fenbendazole could potentially have side effects, and some medications can affect kidney function.

Animal research reveals that high and prolonged doses of Fenbendazole can have adverse effects on the kidneys.  

One study used doses of 500 or 3000 mg per KG for 14 days.  This dose is far higher than what would typically be used in those who are taking Fenbendazole for cancer.

If you're considering using fenbendazole or any other medication for a specific health condition, it's important to consult with a healthcare professional for personalized guidance. 

Those who already have impaired kidney function would need to introduce Fenbendazole very slowly at low doses, and continually assess its effects on kidney function via blood work.  This is why working with a healthcare professional who has specific knowledge of working with fenbendazole and assessing lab values is recommended.

For patients who wish to receive individualized guidance, education, and lab monitoring, it is best to consult an integrative oncology healthcare professional.