Can fenbendazole help with prostate cancer?

Prostate cancer is notorious for eventually developing resistance to standard treatments that block or reduce testosterone, which fuels the growth of these tumors. And like many solid tumors, prostate cancer also has proven stubbornly resistant to newer immunotherapies, which are intended to take the brakes off the immune system’s T cells to get them fighting cancerous invaders. All of which has led scientists and oncologists to look elsewhere for prostate cancer treatment, including Fenbendazole.

Fenbendazole, commonly used as an anthelmintic medication to treat parasitic worm infections in animals, has garnered interest in recent years for its potential anticancer properties. While research is still in its early stages, some studies suggest that fenbendazole may exhibit anticancer effects through various mechanisms.

Studies have shown Fenbendazole could be used for prostate cancer by targeting microtubules, which are structures involved in cell division. Fenbendazole interferes with microtubule function, disrupting the ability of cancer cells to divide and proliferate. This could potentially slow down tumor growth and progression in prostate cancer.

In 2011, a study was done that looked at benzimidazoles, which is the group of drugs Fenben falls under. The study  discovered that certain benzimidazoles, including Fenbendazole, can target aggressive prostate cancer cells without harming normal cells. These drugs work by stopping cancer cells from growing and causing them to die, both in the lab and in animals. When tested in mice with prostate cancer that had spread to the lungs, benzimidazoles helped the mice live longer and slowed down the cancer's growth in their bones. Even more impressive, these drugs still worked against prostate cancer cells that were resistant to standard chemotherapy. Their study clearly suggested that benzimidazoles could be a promising treatment for men with advanced prostate cancer that has spread to other parts of the body.

In another study, Fenbendazole was shown to work effectively in cancer treatments when taken with specific supplementary vitamins. It helps destroy cancer cells by interrupting their sugar uptake, thus helping suppress cancer drug resistance and reducing the size of tumors when taken together with certain vitamin supplements, Fenbendazole was shown to display powerful anti-tumor properties.