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Last update May 2024

Can I use fenbendazole to fight breast cancer?

I have recently been diagnosed with breast cancer and am looking at all of my options when it comes to treatment. Can I use fenbendazole? I know that it fights cancer, but I'm not sure of which specific cancers it can target.

Answered by

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Lisa Miller - Patient Advocate

Fenbendazole is being looked at as a repurposed drug specifically for treating breast cancer because of its ability to adjust the balance of certain molecules in cells, which helps control how cells grow and stay alive. By causing stress in breast cancer cells, there is potential to target and destroy them.

Studies have shown just this, that Fenbendazole can selectively target cancer cells while sparing healthy cells, which is crucial for reducing side effects and improving treatment outcomes. In one such comprehensive study, Fenbendazole was tested on three types of cells: healthy breast cells (MCF-10A), and two types of breast cancer cells (MCF7 – less aggressive, and MDA-MB-231 – more aggressive).

After treating the cells for 48 hours, the study  found that Fenben caused more stress in the highly aggressive MDA-MB-231 cells compared to the less aggressive MCF-7 cells. But in healthy MCF-10A cells, Fenbendazole actually reduced stress levels compared to untreated cells.

These results point to Fenbendazole as a good treatment specifically for aggressive breast cancers.

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