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Last update August 2024

How does drug repurposing fit into precision medicine?

I'm interested in precision medicine and how it tailors treatment to individuals. How does drug repurposing fit into this approach, and does it improve the effectiveness of personalized cancer therapies?

Answered by

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Lisa Miller, Patient Advocate

Drug repurposing aligns well with precision medicine by offering a personalized approach to cancer treatment. This strategy involves using existing drugs, originally developed for other conditions, to target the specific molecular profiles of a patient's cancer.

Key Points:

  • Tailored Treatments: Repurposed drugs expand the range of options available, allowing for treatments to be customized based on the genetic makeup of the cancer.
  • Overcoming Resistance: These drugs can help tackle drug-resistant cancer cells, making treatments more effective.
  • Expanded Options: They provide additional targets for treatment, especially in cancers with diverse genetic profiles.

Benefits and Challenges:

  • Cost and Speed: Repurposed drugs are more affordable and faster to deploy since their safety is already known.
  • Combination Therapies: They are often used alongside standard treatments to enhance overall effectiveness.
  • Challenges: Issues like drug interactions and the need for further clinical trials remain, but the potential benefits are significant.

In summary, drug repurposing is a valuable tool in precision medicine, offering personalized, effective treatment options that can address the limitations of traditional cancer therapies.

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