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Last update August 2024

How Is Metformin Being Used in the Treatment of Cancer?

I've heard about metformin being used in cancer treatment. How is it being utilized, and what are the results so far?

Answered by

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Lisa Miller, Patient Advocate

Metformin, a drug originally made for diabetes, has caught the attention of cancer researchers in the last 15 years. Here’s how it’s being used and what we’ve learned so far:

How Metformin Is Used in Cancer Treatment:

  1. Supporting Other Treatments: Metformin is being tested to see if it can help other cancer treatments, like chemotherapy and radiation, work better.
  2. Preventing Cancer: Researchers are exploring whether Metformin can help prevent certain types of cancer, such as colorectal and breast cancer.
  3. Targeting Cancer: Scientists are studying how Metformin might block the growth of cancer cells by targeting different parts of how they function.

What Was Found So Far:

  • Fighting Cancer Cells: Some studies suggest that Metformin might help stop cancer cells from growing.
  • Lowering Cancer Risk: There’s some evidence that Metformin users might have a lower risk of developing certain cancers.
  • Making Treatments More Effective: Metformin might make cancer treatments like chemotherapy more effective.
  • Ovarian Cancer: A recent study showed that long-term use of Metformin might help in treating ovarian cancer.
  • More Research Needed: Scientists are still conducting studies to see how well Metformin works against different cancers.

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