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Last update June 2024

What are some possible causes of low potassium?

Answered by

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Lisa Miller - Patient Advocate

Low potassium (hypokalemia) is not a disease itself, but rather a symptom or sign of an underlying condition or problem.

Low Potassium can be a sign of:

  1.  Dehydration: excessive potassium loss through the digestive system due to vomiting, diarrhea, or laxative abuse
  2.  Certain medications like diuretics (water pills), antibiotics (amphotericin B, chloroquine), or corticosteroids that increase potassium excretion through the kidney
  3.  Kidney disorders like chronic kidney disease, which impairs the kidneys' ability to regulate potassium levels
  4.  Endocrine disorders like hyperaldosteronism, Cushing's syndrome, or Bartter syndrome that affect potassium regulation
  5.  Excessive sweating, leading to potassium loss through perspiration
  6.  Eating disorders like bulimia that involve frequent purging
  7.  Genetic disorders like hypokalemic periodic paralysis or Gitelman syndrome
  8.  Magnesium deficiency, as magnesium is required for proper potassium regulation

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