What is low dose chemotherapy? 

Low-dose chemotherapy is an emerging strategy for cancer treatment that involves administering chemotherapy drugs at lower doses more frequently or continuously over an extended period.  Here's how it differs from conventional chemotherapy:

1. Dosage: Low-dose chemotherapy typically uses 10-30% of the dosage used in traditional chemotherapy. This significantly reduced dosage aims to minimize side effects while maintaining efficacy.
2. Frequency: Low-dose chemotherapy is administered more often, sometimes on a continuous or frequent regular schedule (such as daily or weekly), usually over a longer period.
3. Side Effects: Due to the lower dosage, patients generally experience fewer and less severe side effects compared to traditional high-dose chemotherapy. This can lead to a better quality of life during treatment.
4. Mechanism of Action: Low-dose chemotherapy may work differently than high-dose regimens. For example, it may have antiangiogenic effects, reducing the blood supply to tumors.
5. Combination with Other Therapies: Low-dose chemotherapy is often combined with other treatments to enhance its effectiveness. For instance, Insulin Potentiation Therapy (IPT) is sometimes used to increase cancer cell sensitivity to the drugs.

Insulin Potentiation Therapy (IPT) is a targeted, metabolic-supported chemotherapy. Dr. Donato Pérez García, the grandson of the inventor, has refined this therapy and administered over 46,000 treatments. IPT increases the permeability of cancer cell membranes using insulin, allowing lower doses of chemotherapy drugs to be more effective. This reduces side effects while targeting cancer cells specifically.