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Last update August 2024

Which Repurposed Drugs Are Effective in Treating Cancer?

Can you provide examples of repurposed drugs that have proven effective in treating cancer?

Answered by

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Lisa Miller, Patient Advocate

Some drugs that were originally made for other health issues are now being used to treat cancer. Here are a few examples:

> Thalidomide: Originally a sedative, it was repurposed and approved in 1998 to treat multiple myeloma, a type of cancer.

> Arsenic Trioxide: Once used as a poison, it was repurposed and approved in 2000 to treat a type of leukemia (a blood cancer).

> Metformin: A diabetes drug that is now being studied for its potential to fight cancers like breast and pancreatic cancer.

> Aspirin: A common pain reliever that might help prevent colorectal cancer.

> Mebendazole: Originally used to treat parasites, this drug has shown promise in treating brain tumors and other cancers.

> Propranolol: A drug for high blood pressure that has shown effectiveness in treating certain cancers, like angiosarcoma.

> Statins: Drugs that lower cholesterol, which may also help in preventing or treating some types of cancer.

These drugs have been repurposed to help treat or prevent cancer. While some are already approved for this use, others are still being studied. Their effectiveness can vary depending on the type of cancer and the individual patient.

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