Are there any known risks or adverse effects associated with using a Rife machine? What should I be aware of before starting treatment with this device?

The rife machine dangers are low and this electromagnetic frequency device is not likely to cause any long-term risks.
The frequency they emit is very low. However, because rife machines are not regulated, the quality of the machine must be considered because virtually anyone can make one. A low-quality machine can put a person at risk for electrical shocks and burns, or the device may not be electrically safe.
Be sure to read reviews of rife machines to compare different brands.