Immunocine Cancer Center
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About Immunocine Cancer Center
Immunocine: Pioneering Personalized Immunotherapy
Established in 2021, the Immunocine Cancer Center is nestled in the serene landscapes of Cancun, Mexico.
Its founding mission was clear: provide groundbreaking immunotherapy to those unable to access ongoing FDA Clinical Trials.
The genesis of Immunocine’s approach traces back to 2006 within the prestigious confines of the Houston Medical Center. Dr. Matthew Halpert and a team of cancer immunologists focused on the development of double-loaded Dendritic Cell Treatment, which has since demonstrated its effectiveness both in meticulous laboratory studies and heartening real-world patient stories.
With a track record of over 150 patients spanning 25 diverse cancer types, Immunocine offers new hope in the battle against cancer.
Immunocine’s treatment is currently going through clinical trials for pancreatic cancer and GB across the US, However, as only a fraction of patients are admitted to those clinical trials, many patients are left without access to these emerging therapies. This gap in treatment accessibility led to the creation of Immunocine in Cancun, Mexico, designed to provide critical therapies to those unable to participate in clinical trials in the United States.
Treatment Eligibility Requirements
Solid Tumors
The clinic currently treats only patients with solid tumors that can be biopsied.
Ability to Travel
Treatment is administered exclusively at the clinic’s facilities in Cancun. Patients unable to travel due to medical conditions or other factors will not be eligible for treatment.
Stable Immune System
A stable, functioning immune system is essential for the success of immunotherapy. Patients with immune deficiencies must restore normal activity before qualifying for treatment.
6-Week Treatment
The treatment protocol requires three sessions over six weeks. Patients can either stay in Cancun for the full duration or visit twice for two-week stays.
Immunocine is now offering before and after liquid biopsies, scans, and labs throughout as ways to track responsiveness.
Why Choose Cancun, Mexico?
Cancun was selected for Immunocine not only for its geographic and aesthetic appeal but also for its strategic importance in offering accessible cancer treatments. This decision acknowledges the challenges associated with the FDA approval process and aims to provide an immediate solution for those in need. Moreover, Cancun’s recognition as a center for medical tourism, with advanced healthcare facilities, makes it an ideal location for such an innovative clinic.
For those at the crossroads of cancer care, searching either for a final ray of hope or the very forefront of immunotherapy, Immunocine stands as a dedicated partner, combining scientific rigor with compassionate care.
Immunocine Cancer Center Cost and Additional Expenses
The treatment is spread over six weeks, which includes a biopsy and three individual treatments, each two weeks apart.
Patients can either choose to stay in Cancun for six weeks or visit twice for two weeks at a time.
The cost of the treatment is $120,000
The price includes:
- Personalized Immunotherapy (Complete Neoantigen Pool): Double Loaded, physiologically activated, matured, autologous Dendritic Cells with patient’s complete tumor neoantigen burden
- Medical Personnel: Oncologist, Radiologist,
Internist, and other specialists as needed - Scientific Personnel: Molecular Biologists, Cell Culture Technologists, Cancer Immunotherapists, and more
- Procedures: US-Guided Injections of Personalized Vaccine, Scans and Imaging, Biopsies, Pathology, Central Line, Aphaeresis, Blood Draws, Vaccine Development, potential intratumoral treatments (e.g. CpG, Microbubbling)
- Medications: Neupogen and Pegasus and symptom management as needed
- Synergistic Supplementation (Case by case): Ex: Metformin, Losartan, etc.
- Intra Cancun Transportation: Cancun driver to handle all medical appointments, trips to airport, and to lodging
- Storage and Follow Up: Dendritic Cell vaccine aliquots properly cryopreserved for future boosts (as able), ongoing and transparent communication with medical team, continued guidance and advice, overseen by medical oncologists, functional medicine specialists, and general physicians. Can not replace primary care.
- Communication: Willing to speak with and coordinate with patient’s home medical team as able
- Data and Analytics: Extensive, but not burdensome, lab testing; liquid biopsy comparisons, radiological analysis, immunological profiling throughout (flow cytometry). All patients receive a treatment summary and data files shortly after completing time in Cancun.
Consultations, tests, apheresis, and vaccine administration is accomplished at a fully licensed medical facility within Cancun. Vaccine is manufactured in an ISO-7 certified, cGMP aligned Laboratory.
Biopsy is accomplished in a fully certified procedure room, and Amerimed Hospital (private, internationally certified) is partnered to help with other medical supervisions that may be needed during time in Cancun.
Patients will also receive pre- and post-treatment bloodwork, biopsy analysis, and CT Scans.
Contact the Clinic
Available Treatments at Immunocine Cancer Center
Double-Loaded Dendritic Cell Therapy
With this therapy, we harness the body’s own immune system to fight cancer more effectively and naturally.
A Quick Step-by-Step Guide:
Step 1: Gathering Intelligence
The journey begins with collecting a small sample of your white blood cells and a piece of the tumor. Through advanced techniques, we break down the tumor cells to extract crucial information: mRNA and cancer antigens. Think of mRNA as the detailed blueprint of the cancer cell, while antigens represent its unique fingerprints.
Step 2: Training the Elite Force
Next, we introduce your dendritic cells, a key player in your immune system, to the cancer’s mRNA and antigens. This is where the “double loading” comes into play.
The mRNA, inserted inside the dendritic cells, acts like a virus alert, providing a comprehensive cancer blueprint. Simultaneously, the antigens, attached to the outside, highlight specific targets. This dual approach equips your dendritic cells with both the face and fingerprints of the enemy, ensuring they know exactly whom to target.
Step 3: Launching the Counterattack
Armed with this knowledge, the dendritic cells trigger a powerful immune response. They analyze the information, inside and out, and upon finding a match, they signal the rest of the immune system to attack. This includes rallying Natural Killer cells and Killer T cells to locate and destroy the cancer cells. This targeted assault is meticulously designed to seek and eliminate only the cancer cells, sparing healthy tissue and reducing side effects.
The treatment takes 14 days of laboratory work to create and is then injected into each patient by an Interventional Radiologist to carefully target lymph nodes near the tumor location.
Main Advantages of Double Loaded Dendritic Cell Therapy
- Precision and Personalization: By targeting cancer cells based on their unique markers, this therapy ensures a highly personalized and precise treatment, tailor-made for your specific cancer.
- Natural and Safe: Utilizing your own cells minimizes the risk of side effects and avoids the introduction of foreign substances or genetically modified cells into your body.
- Lasting Defense: The therapy not only fights existing cancer but also trains your immune system for ongoing vigilance, reducing the likelihood of recurrence.
Meet the Doctors
Conditions Treated
- All types of solid Cancers – Using a novel process replicating a viral infection, Immunocine’s unique treatment initiates a rapid and aggressive immune response against cancer cells throughout the body
General Information
Address
Boulevard Luis Donaldo Coloso (Av Tulum) Manzana, Cancún, MexicoSpoken Languages
- English
- Spanish
Facility
Contact the Clinic
Immunocine Cancer Center Reviews













When I'm asked about my health journey and my experience at Immunicine, I could talk about it non-stop. It was nothing short of extraordinary! After being diagnosed with stage 4 Her2 positive metastatic beast cancer in July 2024 I went right into business mode- ready to do whatever I had to do to beat cancer and get on with my life. At the time, traditional treatment was all I knew or had ever considered. That changed quickly. By complete chance, my husband was seated across from someone at dinner who told him about Immunicine. Within 48 hours, I received a personal phone call from Dr. Halpert. He explained immunotherapy, dendrite cell technology, and the science behind how they approach fighting cancer. - not just by treating it, but actually how my own body's immune system was going to do all the work. That phone call changed everything. From there, the experience was nothing short of incredible. From the first call with Nicole who took all my new patient information with such compassion and understanding, I never doubted this was the right decision. She made the process smooth while her kindness from the very beginning that I was not just another cancer patient, but a person facing something with a life altering situation.
Once I was giving my date to move forward- Nov 4th, 2024- it was full speed ahead. And, other than me making the choice to take care of making airline and hotel accommodations, Robyn & Alejandra took care of everything.That was next level exceptional! They are the very best at putting the patients needs first. As for the Doctors either in front or behind the scene are absolutely incredible, knowledgable, compassionate and truly invested in my health. I always felt I was in the best hands. Immunicine is remarkable. Hands down - I feel like the luckiest person diagnosed with cancer to have been able to be an Immunicine patient and that can say - "I no longer have cancer". It's real! If anyone is searching for an alternative in cancer treatment- Immunicine is the place. PS- I believe any future trips to Cancun will be for vacation only. The Immunicine team will always be in charge of my post -treatment. And while I have one booster left in the freezer- I hope to never need it. BEYOND GRATEFUL.
The Immunocine Clinic and staff are fantastic! They take care of everything you need during your stay and the medical care is outstanding. I have had an excellent response to dendritic cell therapy and my PSA which was 140 prior to treatment is now 0.7. The PSAM-PET CT last fall showed multiple metastases and the latest CT scan last month did not show any evidence of disease.
DCT at Immunocine is truly the best option for those with advanced cancer that have exhausted conventional methods of treatment, or even for those that do not wish to undergo toxic chemo- or radio- therapy, but want their cancer controlled.
I had a fantastic outcome with the clinic. Dendritic cell therapy was administered when I was in a state of regular pain and with an incurable prognosis. Now, 8 months later, all signs of the disease are gone in scans and blood results, and all my daily pains and discomforts are gone. The whole process was expertly handled and the care quality was fantastic. I couldn't be happier with the current result. In addition, I was fortunate enough to get supplementary Keytruda treatment back home. The journey had some unforeseen complications because the treatment had such a tremendous immediate effect, and my immune system went to work to eliminate the disease, causing some local pseudo-progression. However, the immunocine team were there supporting me every step of the way. I would recommend the clinic to absolutely anyone in a similar position as I was.
Hi, l’m Roxy Demartinis and l was diagnosed with ovarian cancer stage 3c in 2019. After doing multiple standard of care treatments (i.e. conventional chemotherapies, low dose chemotherapy) that all failed, I started to research many integrative treatments for the cancer and found Immunocine in 2024. Immunocine seemed like the best science based treatment out there, is validated with scientific publications and clinical trials, and functions in Cancun, Mexico (for patients that are not eligible for the clinical trials). When l applied to Immunocine l discovered that they only accept approximately 15% of applicants. That is when l first realized they were legitimate, as a money-first business would surely find a way to “accept” more clients than that. I admit that I was nervous that I wouldn't be a candidate for Immunocine's double dendritic cell therapy, but I still value their approach. I was informed that there would be no charge for the medical review, another indication of how patient-first they are. I finally found a science based treatment that would specifically target my cancer. Immunocine truly gets your immune system back in the game!
During the application process l was in constant contact with Nicole, a phenomenal patient coordinator in the states who was always kind and compassionate to me and there for me every step of the way! Before l was accepted the founder and CEO, Dr Matt Halpert had a zoom call with me to discuss any questions/concerns l had. Within a week l was accepted. Nicole then directed me to Robyn, the patient concierge in Cancun. Robyn quickly eased my mind in a foreign country. She coordinated all transportation to and from the airport to the hotel, appointments etc. She recommended where to stay. I quickly felt safe, secure and part of the Immunocine family! Robyn met me at every appointment at the Immunocine facilities, whether it was at the hospital, the oncologist office, or the lab. Everyone l met with within the Immunocine team treated me like l was their only patient. Robyn would contact me often even when l didn't have an appointment that day to ask how I felt. I was in contact with Dr Matt Halpert prior to, during my stay in Cancun and after my treatments ended. Immunocine shows a care and compassion for their patients that l have never experienced anywhere else. Doctors came to my hotel room to take blood work. Everything was at my fingertips. Unlike many so-called treatments Immunocine did not say “send a check and we will fix you”. They said let me see if you are a candidate for the double dendritic cell therapy. At this point I am saying to myself that Immunocine is really legitimate and not just after my money.
If you want to get your immune system back in the game and work with a legitimate team that truly cares about you as the patient, then Immunocine is the place for you! They also provided me a lot of data to show how they did indeed fix my immune system, which I can feel is now ‘on’ and ‘working’ and targeting my cancer. Finally, I feel like I have a real shot to beat this thing, and I have obtained a new surrogate family in the process. I cannot say enough good things about Immunocine.
In June 2023, I was diagnosed with bladder cancer. In early August, a cystoscopy was performed to remove the tumor and examine my bladder. It was then confirmed that I had stage 2 bladder cancer, and my oncologist advised bladder removal. I chose bladder preservation instead. My autumn was spent receiving radiation and chemotherapy, with fingers crossed.
On December 26, 2023, I was admitted to the hospital due to difficulty breathing, severe cramping, and generally feeling unwell. I was released in late January 2024 with a drain line coming out of my left lung to remove fluid. My cancer had spread from my bladder to my lung, where there was now a tumor in the pleura, as well as the tumor growing in my bladder again. I was diagnosed with very aggressive stage 4 bladder cancer and told to get my affairs in order. Depression set in.
A few weeks later, my fiancé and I were invited to a Super Bowl party, which I really didn’t care to attend (still not feeling very chipper). I hadn’t yet decided if I wanted to start intense chemotherapy in an effort to extend my life or not. We went, and I met a new friend who introduced me to Immunocine. I reached out to Immunocine the following day, and after some research, the application, video conferences, and acceptance, we were on a plane to Cancun.
From the moment we arrived in Mexico, the Immunocine staff treated us incredibly well. Their drivers took care of 100% of our transportation needs. The clinical staff, doctors, surgeons, oncologists—everyone—did a wonderful and caring job. Our Patient Concierge in Mexico was fantastic. She’s an American who’s lived in Cancun for a long time. We stayed at a Residence Inn near the beach and not too far from the clinic and hospital.
The treatment was relatively painless (at least for me), and I started recovering soon after it was complete. Since the treatment ended and I returned to the US, they have been in contact with me regularly and continue to check on my progress. In early June, feeling that my recovery was going well, we decided to proceed with an earlier planned 2-week vacation to the Isle of Man and Ireland. I’m still not where I want to be but I’m exercising and staying active and am optimistic that I can get back to my normal 62-year-old self soon.
The most important thing I need to state about Immunocine is that, as of August 2024, I am 100% bladder cancer-free! I cannot thank them enough for their care, attention, and innovative treatment that cured me of bladder cancer! These results have been given to me by my MD Anderson oncologist, twice, three months apart.
I recommend Immunocine cancer center to anyone who is serious about getting their immune system in the battle. The science is real and the medical team is wonderful. Immunocine has a culture of compassion and a passion for results.
I was diagnosed with advanced stage unclassified kidney cancer in the summer of 2020. Before coming to Immunocine, I had several surgeries and I experienced several reoccurrences. I was having success with conventional treatment is the states, but those treatments took a major toll on my body and ultimately lead to me experiencing severe internal bleeding. I knew I needed to find a treatment that would be less harmful to my body. My wholistic wellness team (worldview wellness) referred me to Immunocine in the summer of 2023.
Given the unclassified nature of my diagnosis, the thing that appealed to me most about Immunocine is the fact that the treatment is agnostic to the type that of cancer. The treatments train your immune system to recognize and attack your unique malignancy.
Seeking medical attention in a foreign country is certain to be a different experience than you are used to; but the Immunocine team took exceptional care of me while I was there. The team is committed to your success and they keep close contact with you after your treatment is complete.
Overall I am very pleased with the care and the results I experienced. I elected to take chemotherapy after Immunocine got my immune system in the fight, the results were outstanding. It took several months, but eventually my tumor markers went from over 1,500 to undetectable. My young family and I are grateful each and every day for the results I’ve been blessed with.
I am a stage 4 pancreatic cancer patient. My story offers a unique perspective, as I ended up not being treated. I was apprehensive and excited when I was accepted to the program. The plan was to perform a biopsy to collect dendritic cells, followed by electroporation of my pancreatic tumor. The science is solid and I was cautiously optimistic.
I have been undergoing chemotherapy, radiation, and more chemotherapy. I took a break between cycles to go to Immunocine in Cancun. The hospital wasn’t flashy like some I’ve been to, but efficient and clean. Dr Laura was assigned to me, and she stayed by my side the entire time. A friend came with me and we had a plan to bolt if anything felt wrong at any point.
Although I had just had bloodwork a few days before, they wanted to be cautious and check everything again. I was being prepped for surgery, when my platelets came back very low. They determined this unsafe to proceed. This is a common occurrence with my chemo, so we decided to wait and see if I could recover on my own. Dr Laura and a phlebotomist came to my hotel twice that week and tested my blood. I was soon good to go, and they were able to reschedule the procedure. So, I went back to the hospital and started again. Shortly after they started, I was woken from anesthesia and told that they could no longer see my tumor on a Ct scan, as it had continued to shrink, and they could not proceed. I’m writing this review especially for anyone who might question the ethics involved with immunocine. They refunded me most of the money I had paid upfront. They did not take advantage of me, but constantly showed extra caution and care. I can only say good things about my experience. I recommend them one hundred percent, and hope that others can benefit from the work that they are doing in Cancun.
When I 1st arrived at the Immunocine Center (6 weeks ago) I was extremely sick and weak. I had recently been diagnosed with metastatic colon cancer and it was progressing rapidly. I had heard such encouraging stories from people, especially a dear friend who went through the treatment herself, successfully. I wasn't sure if I was "too far gone" to receive help but my family convinced me to go. The 1st few weeks were tough - getting the tests done and waiting for the treatment to be made. The medical team were overwhelmingly supportive and encouraging and kept me physically and emotionally afloat during that 1st couple of weeks. I am now one day away from leaving Cancun and returning home. My pain has substantially decreased (almost no pain at all), my energy is back, my appetite is raging (I couldn't hardly look at food before), I am starting to swim (I was literally in a wheelchair to get around), many of the side effects of the cancer have subsided. Amazingly, my last bloodwork results just came back showing a drastic reduction in my cancer markers. It's been 6 weeks and I already feel like I'm getting my life back. I know that my healing process is a marathon race and not a sprint but I am beyond encouraged and filled with hope that I have a future awaiting me. I couldn't be more grateful to this medical team that stood by me every step of the way with kindness, gentleness, encouragement and never letting me lose hope. My family and I are forever grateful for your expertise and personalized care.
